H-His-His-Leu-Gly-Gly-Ala-Lys-Gln-Ala-Gly-Asp-Val-OH,89105-94-2,十二肽 (HHLGGAKQAGDV,H12)
序列(三字母):
H-His-His-Leu-Gly-Gly-Ala-Lys-Gln-Ala-Gly-Asp-Val-OH
序列(单字母):
HHLGGAKQAGDV
分子式:
C50H80N18O16
分子量:
1189.3
CAS#:
89105-94-2
合成方法:
Synthetic
存储条件:
-20 °C,避光,干燥
应用:
HematologyRegenerative Medicine
产品描述:
Fibrinogen Binding Inhibitor Peptide 是一种十二肽 (HHLGGAKQAGDV,H12),是纤维蛋白原 γ 链羧基末端序列 (γ400-411),Fibrinogen Binding Inhibitor Peptide是活化糖蛋白 (GP) IIb/IIIa 配体的特异性结合位点。它是纤维蛋白原,纤连蛋白和血管性血友病因子(vWF)与凝血酶-/ADP-刺激血小板结合的强有效的抑制剂。结合血小板活化,Fibrinogen Binding Inhibitor Peptide也被用来研究磷酸化过程。
参考文献:
1.Okamura Y, et al. Release abilities of adenosine diphosphate from phospholipid vesicles with different membraneproperties and their hemostatic effects as a platelet substitute.J Control Release. 2010 Dec 20;148(3):373-9.
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